The fate of concanavalin A (Con A) bound to normal and enucleated L cells was followed at the ultrastructural level over a 20-h period. In both enucleates and normal cells the Con A is seen to be distributed in a uniform manner over the entire cell surface following a 30-min pulse with a low concentration of Con A. In the subsequent chase period the cells then aggregate the Con A and Con A sites into large clusters on the cell membrane. The cells then phagocytoze the Con A and large phagocytic vacuoles containing it are observed. Thus, enucleated cells are capable of phagocytozing Con A and its sites in the same manner as normal cells.
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JOURNAL ARTICLE| 01 December 1976
Phagocytosis of concanavalin A in normal and enucleated cultures of mammalian cells
Online Issn: 1477-9137
Print Issn: 0021-9533
© 1976 by Company of Biologists
J Cell Sci (1976) 22 (3): 623–632.
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G.E. Wise; Phagocytosis of concanavalin A in normal and enucleated cultures of mammalian cells. J Cell Sci 1 December 1976; 22 (3): 623–632. doi: https://doi.org/10.1242/jcs.22.3.623
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