The requirement for a nucleolus in the expression of structural genes of nuclear viruses was examined by means of experiments in which the nucleolus or other parts of the nucleus was inactivated by a microbean of unltraviolet light. These experiments showed that the expression of such genes is not dependent on cucleolar function. This conclusion is discussed in the light of previous experiments in which similar inactiviation of nucleolus was shown to prevent the expression of cellular structural genes.
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JOURNAL ARTICLE| 01 May 1975
Effects of discrete nuclear u.v-microbeam irradiation on herpes virus and SV40 infection
Online Issn: 1477-9137
Print Issn: 0021-9533
© 1975 by Company of Biologists
J Cell Sci (1975) 17 (3): 531–538.
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I.I. Deak, V. Defendi; Effects of discrete nuclear u.v-microbeam irradiation on herpes virus and SV40 infection. J Cell Sci 1 May 1975; 17 (3): 531–538. doi: https://doi.org/10.1242/jcs.17.3.531
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