A round-up of preLights posts related to preprints in cell biology, posted between mid-January 2022 and mid-April 2022
State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold by Roney & Ovchinnikov
AlphaFold may not be ‘just’ a pattern recognition algorithm, but may have also learnt about the energetics of protein folding
Selected by Kieran Didi, read the preLight here
Dissecting β-cardiac Myosin and Cardiac Myosin-Binding Protein C Interactions using a Nanosurf Assay by Touma et al.
Nanosurf assay: a new tool to probe how the elusive myosin-binding protein C regulates cardiac contractility
Selected by Neha Nandwani, read the preLight here
Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response by Mehl et al.
Breaking the borders to macrophage activation
Selected by Roberto Amadio, read the preLight here
Local IL-17 orchestrates skin aging by Solá et al.
Interleukin 17 is behind wrinkles and loss of hair
Selected by Andrea Irazoki, read the preLight here
Mechanical stretch regulates micropinocytosis in Hydra vulgaris
Hydra stretches and Hydra gulps
Selected by Mugdha Sathe, read the preLight here
ATM-dependent formation of a novel chromatin compartment regulates the response to DNA double strand breaks and the biogenesis of translocations by Arnould et al.
Diving into the ‘D’ compartment of DSB repair
Selected by Jennifer Ann Black, read the preLight here
The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination
E-cadherins Assemble: distinct Ca2+ signalling pathways control E-cadherin remodelling in Drosophila epithelial cell invasion
Selected by Holly Smith, read the preLight here
cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status by MacDonald et al.
Inflammation upon DNA damage: it takes two to tango
Selected by Roberto Amadio, read the preLight here
Bacterial filamentation is an in vivo mechanism for cell-to-cell spreading by Tran et al.
Skilful pathogens: a bacterium that forms filaments to colonise its nematode host
Selected by Angika Basant, read the preLight here
