Imaging beyond the super-resolution limits using ultrastructure expansion microscopy (UltraExM)by Gambarotto et al.

Go beyond the limits! Gambarotto et al. report a novel method of near-native expansion microscopy (UltraExM), which goes beyond the super-resolution limits and reveals ultrastructural details of centrioles.

Selected by Satish Bodakuntla. Read the preLight here

A minimal “push-pull” bistability model explains oscillations between quiescent and proliferative cell states by Krishna and Laxman

How do cells decide when to grow and divide? Resource availability, cell history, and neighboring cell state drive oscillations between quiescence and proliferation.

Selected by Lauren Neves. Read the preLight here

OptoGranules reveal the evolution of stress granules to ALS-FTD pathologyby Zhang et al.

Optogenetic tool to identify and study how chronic stress causes the formation of pathogenic inclusions in neurodegenerative diseases.

Selected by Srivats Venkataramanan. Read the preLight here

A new calcium-activated dynein adaptor protein, CRACR2a, regulates clathrin-independent endocytic traffic in T cellsby Wang et al.

A CRACR of a story… the identification of CRACR2a as a calcium responsive dynein adaptor involved in endocytosis at the T cell immune synapse.

Selected by Nicola Stevenson. Read the preLight here

Mitotic chromosome alignment is required for proper nuclear envelope reassemblyby Fonseca et al.

Line up! Alignment at the metaphase plate spatially clusters chromosomes to ensure proper nuclear formation after segregation

Selected by Maiko Kitaoka. Read the preLight here

Structural Basis of Tubulin Recruitment and Assembly by Tumor Overexpressed Gene (TOG) domain array Microtubule Polymerasesby Nithiananatham et al.


Roles for tubulin recruitment and self-organization by TOG domain arrays in Microtubule plus-end tracking and polymeraseby Cook et al.

Squaring up to tubulin: A new mechanism for tubulin recruitment and polymerisation through the microtubule polymerase Alp14.

Selected by the Welburn lab. Read the preLight here

Spatiotemporally controlled Myosin relocalization and internal pressure cause biased cortical extension to generate sibling cell size asymmetryby Pham et al.

The right cell at the right size: how myosin-dependent tension and hydrostatic pressure coordinate to achieve physical asymmetry.

Selected by Giuliana Clemente. Read the preLight here

Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loadingby Gilbert et al.

A dynamic approach for the culture of cells and its impact upon mechanobiology.

Selected by Rebecca Quelch. Read the preLight here

A robust method for transfection in choanoflagellates illuminates their cell biology and the ancestry of animal septinsby Booth et al.

The development of transfection technologies in choanoflagellates sheds light on ancestral cell scaffolding machinery.

Selected by Maya Emmons-Bell. Read the preLight here