The LIM domain-containing Ajuba proteins are involved in numerous cellular processes, most prominently the regulation of apical cell junctions or adherens junctions. However, the in vivo mechanisms of action for three vertebrate Ajuba family proteins – Limd1, Ajuba and Wilms tumor-1-interacting protein (Wtip) – remain poorly understood. Now, Sergei Sokol and co-workers (Chu et al., 2018) examine the role of Wtip during apical constriction, a key process accompanying neural tube closure in Xenopus embryos. The authors find that loss of Wtip blocks apical constriction and leads to neural tube defects. A tagged Wtip fusion protein changed localization from a punctate pattern at epidermal cell junctions to a linear pattern at junctions in the neuroectoderm, which likely depends on apical constriction triggered by the actin-binding protein Shroom3. Specifically, the C-terminus of Wtip associates with Shroom3 to interfere with its activity. Furthermore, Wtip relocalization during neurulation responds to actomyosin-generated tension, since a reduction of myosin II activity reverses the linear localization to a punctate pattern. This work suggests a role for Wtip as a cytoskeletal adaptor for actomyosin contractility at apical junctions during vertebrate neural tube closure.