Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

We are welcoming submissions for our upcoming special issue: Cilia and Flagella: from Basic Biology to Disease. This issue will be coordinated by two Guest Editors: Pleasantine Mill (University of Edinburgh) and Lotte Pedersen (University of Copenhagen). Submission deadline: 1 March 2025.

We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate the Spring Meetings of the BSCB and the BSDB, the JEB Symposium Sensory Perception in a Changing World and a DMM programme on antimicrobial resistance. Find out more and register your interest to join us in March 2025 in Liverpool, UK. The deadline for abstract submission and early-bird registration is 17 January 2025.

In this Review, Johanna Grinat and colleagues provide an evolutionary perspective of histones, nuclear chromatin and extracellular chromatin biology, describing the known extranuclear and extracellular functions of histones.

Early-career researchers - working in an area covered by JCS - who would like to attend a microscopy training course, please apply. Deadline dates for 2025 applications: 7 March 2025 (decision by week commencing 21 April 2025) and 6 June 2025 (decision by week commencing 28 July 2025).

All stakeholders – from those working in the lab to those providing funding and infrastructure – have an important role to play to becoming more sustainable. In this Essay, Julie Welburn discusses what lab users can collectively do to transform biomedical research into a discipline that is significantly and positively sustainable.