Nuclear receptors are ligand-activated transcription factors that bind to hormones such as oestrogen and progesterone, as well as a variety of other ligands, including vitamin D3 and prostaglandin J2. They form a large gene family — C. elegans alone has >270 members — and many have no known ligand. In Cell Science at a Glance, Marc Robinson-Rechavi and co-workers provide a brief introduction to these receptors, including a phylogenetic analysis of the known family members and a summary of their mode of action (see p. 585 +poster).
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IN THIS ISSUE| 15 February 2003
A guide to nuclear receptors
Online Issn: 1477-9137
Print Issn: 0021-9533
© The Company of Biologists Limited 2003
J Cell Sci (2003) 116 (4): e406.
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A guide to nuclear receptors. J Cell Sci 15 February 2003; 116 (4): e406. doi:
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