A factor diffuses from Escherichia coli that temporarily or permanently prevents separate pre-aggregation cells of Dictyostelium discoideum from forming aggregation centres or streams. Centres are inhibited at a greater distance from the bacteria than are streams. The inhibitor does not support the slime-mould's growth, and it has different properties from previously discovered aggregation-centre inhibitors released by the amoebae themselves. The factor, as produced, does not inhibit Polysphondylium violaceum cells from forming centres or streams. Yet although E. coli itself attracts pre-aggregation P. violaceum cells, it does not mimic a P. violaceum aggregate in inducing them to form streams.
JOURNAL ARTICLE| 01 December 1966
Inhibition of Aggregation of the Slime Mould Dictyostelium Discoideum by a Factor Diffusing from Escherichia Coli
B. M. SHAFFER
Department of Zoology, University of Cambridge
Received: 17 Aug 1966
Online Issn: 1477-9137
Print Issn: 0021-9533
Copyright © 1966 The Company of Biologists Ltd.
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B. M. SHAFFER; Inhibition of Aggregation of the Slime Mould Dictyostelium Discoideum by a Factor Diffusing from Escherichia Coli. J Cell Sci 1 December 1966; 1 (4): 391–400. doi: https://doi.org/10.1242/jcs.1.4.391
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