Complementation between temperature-sensitive (ts) variants of Balb/c-3T3 defective in the G1 phase of its cell cycle was measured in the [1H]thymidine-labelling indices of the multinucleated cells during incubation at the restricted temperature (38 °C) following cell fusion. One ts variant from each group along the length of the G1 phase was tested for complementation. Varying degrees of complementation were observed between the 4 ts variants tested, judging by the time of entry into S-phase and the degree of synchrony attained. At least 3 complementation groups were discernible.

© 1979 by Company of Biologists
1979
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