The formation of two daughter cells requires accurate cytokinesis. The mitotic spindle marks the division plane in animal cells and delivers signals to the equatorial cortex through central spindle and astral microtubules. In anaphase, the centralspindlin complex accumulates on overlapping antiparallel microtubules of the central spindle. Centralspindlin comprises the mitotic kinesin-like protein 1 (MKLP1) and MgcRacGAP; the latter interacts with the RhoA guanine nucleotide exchange factor Ect2 to control RhoA activity, which is essential for cytokinesis. On page 1809, Ann Miller and co-workers find that MgcRacGAP also localises to astral microtubule plus ends at the equatorial cell cortex in Xenopus laevis embryos. Within MgcRacGAP, the authors identify an SxIP motif to which EB proteins that track the plus end of microtubules can bind. Mutations in the SxIP motif lead to the loss of both MgcRacGAP tracking with EB3 and equatorial accumulation of MgcRacGAP. Furthermore, astral microtubules are disorganised when...

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