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Keywords: eQTL
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Journal Articles
Georg W. Otto, Pamela J. Kaisaki, Francois Brial, Aurélie Le Lay, Jean-Baptiste Cazier, Richard Mott, Dominique Gauguier
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (7): dmm038539.
Published: 15 July 2019
... analysis of genome-wide gene transcription in the kidneys of F2 offspring from the Goto-Kakizaki (GK) rat model of type 2 diabetes and normoglycaemic Brown Norway (BN) rats. We mapped 2526 statistically significant expression quantitative trait loci (eQTLs) in the cross. More than 40% of eQTLs mapped...
Includes: Supplementary data
Journal Articles
From integrative genomics to systems genetics in the rat to link genotypes to phenotypes
Open AccessIn collection:
Rat as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2016) 9 (10): 1097–1110.
Published: 1 October 2016
... strategies [such as expression quantitative trait loci (eQTLs) mapping] and concluding with the most sophisticated gene network-based analyses in multiple systems and disease states. Although not limited to studies that have been directly translated to humans, we will focus particularly on the successful...