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Keywords: dnSNARE
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Journal Articles
Modulation of SNARE-dependent exocytosis in astrocytes improves neuropathology in Huntington's disease
Open AccessIn collection:
Neurodegenerative Disorders
Annesha C. King, Emily Payne, Emily Stephens, Jahmel A. Fowler, Tara E. Wood, Efrain Rodriguez, Michelle Gray
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (11): dmm052002.
Published: 11 November 2024
... astrocytes to determine whether reducing SNARE-dependent exocytosis from astrocytes could rescue neuropathological changes in vivo . We observed significant protection against striatal atrophy and no significant rescue of cortical atrophy in BACHD/dnSNARE mice compared to BACHD mice. Amino acid transporters...
Includes: Supplementary data
