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Keywords: cAMP
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Journal Articles
Dis Model Mech (2019) 12 (2): dmm037085.
Published: 20 February 2019
... identifiable descending neurons through the activation of serotonin 1A receptors and a subsequent decrease in cyclic adenosine monophosphate (cAMP) levels. RNA sequencing revealed that changes in the expression of genes that control axonal guidance could be a key factor determining the serotonin effects during...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2017) 10 (5): 597–603.
Published: 01 May 2017
... complement. Neuron-derived ATP acts as an alarm messenger for Schwann cells, where it induces the activation of intracellular pathways, including calcium signaling, cAMP and CREB, which, in turn, produce signals that promote nerve regeneration. These results contribute to defining the cross-talk taking place...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2015) 8 (1): 65–80.
Published: 01 January 2015
... in cultured endothelial cells derived from subcutaneous sponge implants (SIECs) of control and Goto-Kakizaki rats. Ensuing data from diabetic SIECs demonstrated a marked upregulation in cAMP-PKA-CREB signaling, possibly stemming from increased expression of adenylyl cyclase isoforms 3 and 8, and...