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Keywords: Xenografts
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Journal Articles

A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

In collection:
Cancer , Tools and Resources for Mouse Studies
Lukas Krasny, Philip Bland, Jessica Burns, Nadia Carvalho Lima, Peter T. Harrison, Laura Pacini, Mark L. Elms, Jian Ning, Victor Garcia Martinez, Yi-Ru Yu, Sophie E. Acton, Ping-Chih Ho, Fernando Calvo, Amanda Swain, Beatrice A. Howard, Rachael C. Natrajan, Paul H. Huang
Journal: Disease Models & Mechanisms
Dis Model Mech (2020) 13 (7): dmm044586.
https://doi.org/10.1242/dmm.044586
Published: 14 July 2020
... MouseRefSWATH to develop an analytical pipeline for species-specific deconvolution of proteomic alterations in human tumour xenografts (XenoSWATH). This method overcomes the challenge of high sequence similarity between mouse and human proteins, facilitating the study of host microenvironment-tumour...
View article titled, A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour <span class="search-highlight">xenografts</span>
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Includes: Supplementary data