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Keywords: X-chromosome inactivation
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Journal Articles

X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities

Open Access
In collection:
Neurodegenerative Disorders
Jakub Sikora, Jennifer Leddy, Maria Gulinello, Steven U. Walkley
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (1): 13–23.
https://doi.org/10.1242/dmm.022780
Published: 1 January 2016
... the wild-type and mutant SLC9A6 alleles mosaically as a result of X-chromosome inactivation (XCI), have not yet been systematically characterized. Slc9a6 knockout mice (Slc9a6 KO) were generated by insertion of the bacterial lacZ /β-galactosidase (β-Gal) reporter into exon 6 of the X-linked gene. Mutant...
View articletitled, X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities
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Includes: Supplementary data