... associated with the human ch16p11.2 microdeletions and microduplications. Maz Sfrp2 Wnt pathway Eye CNV 16p11.2 Formation of the eye is an evolutionarily conserved developmental process that leads to morphogenesis of the retina, lens and associated eye structures. Disturbances within...

.... ( 2011 ). Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88 . Proc. Natl. Acad. Sci. USA   4570 - 4577 . 10.1073/pnas.1000072107 Chera , S. and Herrera , P. L. ( 2016 ). Regeneration of pancreatic...

... pathways and the accumulation of mutant huntingtin and SOD1. p53 is a pleiotropic molecule that binds huntingtin ( Steffan et al., 2000 ), interacts with ERK and Wnt pathways and plays a role in oxidative stress. Data mining using the STRING 9.1 database ( Franceschini et al., 2013 ) revealed that all...

... Wnt pathway Fibrosis Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), represent a significant health burden worldwide owing to their progressive nature and the current lack of curative treatments. Therapeutic options...

... on the alterations we found in the expression of Apc and β-catenin, the Wnt pathway seems to be implicated in the induction of ileo-caecal adenocarcinoma by C. parvum . Furthermore, in neoplastic lesions, a stabilization of β-catenin, an abnormal accumulation at a basolateral position and a dilation...