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Keywords: Wnt/β-catenin signaling
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Journal Articles

Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development

In collection:
Developmental Disorders
Sung-Eun Kim, Pooja J. Chothani, Rehana Shaik, Westley Pollard, Richard H. Finnell
Journal: Disease Models & Mechanisms
Dis Model Mech (2023) 16 (11): dmm050277.
https://doi.org/10.1242/dmm.050277
Published: 28 November 2023
... and Wnt/β-catenin signaling in spinal neural tube development. Gpr161 Pax3 Wnt/β-catenin signaling Craniofacial development Spinal neural tube National Institutes of Health HD093758 HD067244 Baylor College of Medicine http://dx.doi.org/10.13039/100007915...
View article titled, Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development
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Includes: Supplementary data
Journal Articles

The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice

In collection:
Developmental Disorders
Tianyu Zhao, Moira McMahon, Kurt Reynolds, Subbroto Kumar Saha, Arjun Stokes, Chengji J. Zhou
Journal: Disease Models & Mechanisms
Dis Model Mech (2022) 15 (6): dmm049517.
https://doi.org/10.1242/dmm.049517
Published: 10 June 2022
... signaling in neural tube closure remain unresolved. We previously demonstrated that β-catenin signaling is required for posterior neuropore (PNP) closure. In the current study, conditional ablation of Lrp6 in dorsal PNP caused spinal NTDs with diminished activities of Wnt/β-catenin signaling and its...
View article titled, The role of Lrp6-mediated <span class="search-highlight">Wnt</span>&#x2F;<span class="search-highlight">β</span>-<span class="search-highlight">catenin</span> <span class="search-highlight">signaling</span> in the development and intervention of spinal neural tube defects in mice
Open the PDF for The role of Lrp6-mediated <span class="search-highlight">Wnt</span>/<span class="search-highlight">β</span>-<span class="search-highlight">catenin</span> <span class="search-highlight">signaling</span> in the development and intervention of spinal neural tube defects in mice in another window
Journal Articles

Intraluminal valves: development, function and disease

Xin Geng, Boksik Cha, Md. Riaj Mahamud, R. Sathish Srinivasan
Journal: Disease Models & Mechanisms
Dis Model Mech (2017) 10 (11): 1273–1287.
https://doi.org/10.1242/dmm.030825
Published: 1 November 2017
... and treatment of valve disorders. Wnt/β-catenin signaling Calcific aortic valve disease Lymphatic vasculature Mechanobiology Valves The survival of multicellular organisms depends on the ability of their cells to receive nutrients and to dispose of waste. In vertebrates, two interconnected...
View article titled, Intraluminal valves: development, function and disease
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