.... ( 2004 ). Interactions between Sox9 and β-catenin control chondrocyte differentiation . Genes Dev. 18 , 1072 - 1087 . 10.1101/gad.1171104 Angers , S. and Moon , R. T. ( 2009 ). Proximal events in Wnt signal transduction . Nat. Rev. Mol. Cell Biol. 10 , 468 - 477...

... of FRT, that manifested as a contorted caudal vagina and abrogated vaginal–urogenital sinus fusion in neonates. The MAP3K1 kinase domain is required for optimal activation of the Jun-N-terminal kinase (JNK) and cell polarity in the MD epithelium, and for upregulation of WNT signaling in the mesenchyme...

... , M. , Weeks , R. J. , Morison , I. M. and Reeve , A. E. ( 2009 ). Canonical WNT signalling determines lineage specificity in Wilms tumour . Oncogene 28 , 1063 - 1075 . 10.1038/onc.2008.455 Fukuzawa , R. , Anaka , M. R. , Morison , I. M. and Reeve , A. E...

... syndrome are genetically heterogeneous, and the common theme is that all the mutations lie in genes in Wnt signaling pathways. Cases diagnosed with Robinow syndrome do survive to adulthood with distinct skeletal phenotypes, including limb shortening and craniofacial abnormalities. Here, we focus...

... tumor cell repopulation. The level of secreted frizzled related protein-1 (SFRP1), hedgehog and Gli1 were increased in irradiated cells. Our results highlight the interaction between Wnt and SHH signaling pathways in dying tumor cells and suggest that downregulation of Wnt signaling after SHH activation...