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Keywords: Visual system
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Journal Articles
TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
Open AccessIn collection:
Neurodegenerative Disorders
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (2): dmm047548.
Published: 11 February 2021
... sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The downstream in vivo cellular effects of this mislocalization are not well understood. To investigate the impact of mislocalized TDP-43 on neuronal cell bodies, axons and axonal terminals, we utilized the mouse visual system to create a new...
Includes: Supplementary data