...Amanda Miles; Clarke Blair; Andrew Emili; Vincent Tropepe ABSTRACT Blindness associated with Usher syndrome type 1 (USH1) is typically characterized as rod photoreceptor degeneration, followed by secondary loss of cones. The mechanisms leading to blindness are unknown because most genetic mouse...

... syndrome, the leading cause of human deafness and blindness. In Drosophila , some Usher syndrome proteins appear to physically interact in protein complexes that are similar to those described in mammals. This functional conservation highlights a rational role for Drosophila as a model for studying hearing...

...://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Usher syndrome Cancer Individualized medicine Muscular dystrophy Tuberculosis Since its establishment as a vertebrate model...

...Bernardo Blanco-Sánchez; Aurélie Clément; Javier Fierro, Jr; Philip Washbourne; Monte Westerfield Usher syndrome (USH), the leading cause of hereditary combined hearing and vision loss, is characterized by sensorineural deafness and progressive retinal degeneration. Mutations in several different...