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Keywords: Transgenics
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Journal Articles

Preclinical models for obesity research

In collection:
Metabolic Disorders , Rat as a Disease Model
Perry Barrett, Julian G. Mercer, Peter J. Morgan
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (11): 1245–1255.
https://doi.org/10.1242/dmm.026443
Published: 1 November 2016
.... Summary: We review genetic models of obesity, their optogenetic and chemogenetic successors, and the use of dietary manipulations and meal-feeding regimes. Binge eating Epigenetics Obesity Transgenics Scottish Government 266408 Biotechnology and Biological Sciences Research...
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Journal Articles

New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein

Ana Isabel Garcia Diaz, Ben Moyon, Philip M. Coan, Neza Alfazema, Lara Venda, Kevin Woollard, Tim Aitman
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (4): 463–471.
https://doi.org/10.1242/dmm.024208
Published: 1 April 2016
..., respectively. Novel transgenic (Tg) strains add research opportunities and increase scientific value to well-established rat models. We have created two novel Tg strains using Sleeping Beauty transposon germline transgenesis, ubiquitously expressing green fluorescent protein (GFP) under the rat elongation...
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Includes: Supplementary data