... intracranial lesions. Non-small cell lung cancers (NSCLCs) are the most likely of all neoplasms to metastasize to the brain, with up to 60% of patients developing CNS metastases during the disease process. Targeted therapies such as tyrosine kinase inhibitors (TKIs) have helped reduce lung cancer mortality...

... progenitors. Outcomes remain poor for T-ALL patients who have either primary resistance to standard-of-care chemotherapy or disease relapse. Notably, there are currently no targeted therapies available in T-ALL. This lack of next-generation therapies highlights the need for relevant preclinical disease...

... that the original work is properly attributed. Cancer stem cell Fluorescence Intratumoral Single cell Targeted therapy Tumor Cancer progression is a dynamic and stochastic process in which heritable genotypic and phenotypic changes are randomly produced as a result of increased genomic...