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Keywords: TFAM
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Journal Articles
In collection:
Advanced in vitro models
Manuel J. Del Rey, Carolina Meroño, Cristina Municio, Alicia Usategui, María Mittelbrunn, Inés García-Consuegra, Gabriel Criado, José L. Pablos
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (8): dmm048995.
Published: 25 August 2021
.... Mitochondrial transcription factor A (TFAM) plays a critical role in maintaining mtDNA integrity and function. Taking advantage of Tfam fl/fl UBC-Cre/ER T2+/+ mice to investigate mitochondrial dysfunction in the stromal cell component, we describe an inducible in vitro model of mitochondrial dysfunction...
Includes: Supplementary data