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Keywords: Sterilizing immunity
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Journal Articles
Hanna Luukinen, Milka Marjut Hammarén, Leena-Maija Vanha-aho, Aleksandra Svorjova, Laura Kantanen, Sampsa Järvinen, Bruno Vincent Luukinen, Eric Dufour, Mika Rämet, Vesa Pekka Hytönen, Mataleena Parikka
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (1): dmm031658.
Published: 29 January 2018
.... The protective effects of HKLm are abolished when the injected material is pretreated with nucleases or proteinase K. Importantly, HKLm priming significantly increases the frequency of clearance of M. marinum infection by evoking sterilizing immunity (25 vs 3.7%, P =0.0021). In this study, immune priming...
Includes: Supplementary data