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Keywords: Sonic hedgehogClose
Laura A. Runck, Anna Method, Andrea Bischoff, Marc Levitt, Alberto Peña, Margaret H. Collins, Anita Gupta, Shiva Shanmukhappa, James M. Wells, Géraldine Guasch
Journal: Disease Models & Mechanisms
Dis Model Mech (2014) 7 (4): 483–493.
Published: 01 April 2014
... and morphogenesis. Here we compared human and mouse cloaca development and retrospectively identified that early mis-patterning of the embryonic cloaca might underlie the most severe forms of anorectal malformation in humans. In mouse, we identified that defective sonic hedgehog (Shh) signaling...
Includes: Supplementary data