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Keywords: Respiration
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Journal Articles
Journal Articles
Dis Model Mech (2017) 10 (10): 1261–1271.
Published: 1 October 2017
... mitochondrial respiration, the loss or reduction of function of DJ-1 in Parkinson's disease cells produces defects in particular endocytic pathways, downstream vesicle trafficking and related processes. At least 17 other Parkinson's disease-related proteins also play normal and cytopathological roles...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (11): 1295–1305.
Published: 1 November 2016
... of post-mortem Parkinson's disease (PD) brains, pharmacological and genetic models of PD have suggested that two fundamental interacting cellular processes are impaired – proteostasis and mitochondrial respiration. We have re-examined the role of mitochondrial dysfunction in lymphoblasts isolated from...
Includes: Supplementary data
Journal Articles