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Keywords: Protoporphyrin IX (PPIX)
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Journal Articles
Dis Model Mech (2017) 10 (3): 225–233.
Published: 1 March 2017
... into protoporphyrin IX (PPIX) to form heme. Excitation of accumulated PPIX by light generates oxygen radicals that evoke excessive pain and, after longer light exposure, cause ulcerations in exposed skin areas of individuals with EPP. Moreover, ∼5% of the patients develop a liver dysfunction as a result of PPIX...
Includes: Supplementary data