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Keywords: Proteomics
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Journal Articles
Dis Model Mech (2023) 16 (3): dmm049863.
Published: 20 March 2023
... conservation and experimental tractability. Here, a paradigm enabling C. elegans qHTS using 384-well microtiter plate laser-scanning cytometry is described, in which GFP-expressing organisms revealing phenotype-modifying structure–activity relationships guide subsequent life-stage and proteomic analyses...
Includes: Supplementary data
Journal Articles
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Rare Disease
Dis Model Mech (2022) 15 (12): dmm049651.
Published: 13 December 2022
... membrane-bound vacuoles containing diverse storage material and hyperglycosylation of the lysosomal LAMP1 protein. Proteomic analysis showed increase in lysosomal-related proteins and many ribosomal subunit proteins in CLN3 neurons, accompanied by downregulation of proteins related to axon guidance...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Dis Model Mech (2020) 13 (5): dmm044081.
Published: 17 May 2020
... quantitative proteomic analysis indicated anemia of these rats, which presented with significant downregulation of hemoglobin and haptoglobin. Decreased hemoglobin and increased RDW were further observed in Rffl TD through complete blood count. Next, a systematic temporal assessment detected an early increased...
Includes: Supplementary data
Journal Articles
Journal Articles