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Keywords: Protein disulfide isomerase
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Journal Articles
In collection:
Drug Discovery
Lucía F. Zacchi, John C. Dittmar, Michael J. Mihalevic, Annette M. Shewan, Benjamin L. Schulz, Jeffrey L. Brodsky, Kara A. Bernstein
Journal:
Disease Models & Mechanisms
Dis Model Mech (2017) 10 (9): 1129–1140.
Published: 1 September 2017
..., we identified 365 deletion strains with altered torsinAΔE steady-state levels. One notable hit was EUG1 , which encodes a member of the protein disulfide isomerase family (PDIs). PDIs reside in the ER and catalyze the formation of disulfide bonds, mediate protein quality control and aid in nascent...
Includes: Supplementary data
