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Keywords: Prominin-1
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Journal Articles
In collection:
Neurodegenerative Disorders
Yuka Kobayashi, Shizuka Watanabe, Agnes Lee Chen Ong, Manabu Shirai, Chiemi Yamashiro, Tadahiko Ogata, Fumiaki Higashijima, Takuya Yoshimoto, Takahide Hayano, Yoshiyuki Asai, Noriaki Sasai, Kazuhiro Kimura
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (11): dmm048962.
Published: 24 November 2021
... photoreceptor death in the retina and are often associated with genetic mutations, including those in the prominin-1 ( Prom1 ) gene. Prom1 -knockout (KO) mice recapitulate key features of these diseases including light-dependent retinal degeneration and constriction of retinal blood vessels. The mechanisms...
Includes: Supplementary data