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Keywords: Poly-GR
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Journal Articles
Dis Model Mech (2021) 14 (11): dmm049092.
Published: 01 December 2021
...) and amyotrophic lateral sclerosis (ALS). This repeat expansion can be translated into dipeptide repeat proteins (DPRs), and distribution of the poly-GR DPR correlates with neurodegeneration in postmortem C9FTD/ALS brains. Here, we assessed poly-GR toxicity in zebrafish embryos, using an annexin A5-based...
Includes: Supplementary data