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Keywords: Podocyte
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Journal Articles
In collection:
Drosophila as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (12): dmm050223.
Published: 27 December 2023
...Jun-yi Zhu; Jin-Gu Lee; Yulong Fu; Joyce van de Leemput; Patricio E. Ray; Zhe Han ABSTRACT People of African ancestry who carry the APOL1 risk alleles G1 or G2 are at high risk of developing kidney diseases through not fully understood mechanisms that impair the function of podocytes. It is also...
Journal Articles
Rafael Luiz Pereira, Raphael José Ferreira Felizardo, Marcos Antônio Cenedeze, Meire Ioshie Hiyane, Ênio José Bassi, Mariane Tami Amano, Clarice Sylvia Taemi Origassa, Reinaldo Correia Silva, Cristhiane Fávero Aguiar, Sylvia Mendes Carneiro, João Bosco Pesquero, Ronaldo Carvalho Araújo, Alexandre de Castro Keller, Renato C. Monteiro, Ivan Cruz Moura, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Journal:
Disease Models & Mechanisms
Dis Model Mech (2014) 7 (6): 701–710.
Published: 1 June 2014
... with the B2RBK antagonist HOE-140 and the B1RBK antagonist DALBK. Here, we show that the blockage of B2RBK with HOE-140 protects mice from the development of FSGS, including podocyte foot process effacement and the re-establishment of slit-diaphragm-related proteins. However, B2RBK-knockout mice were...
Includes: Supplementary data