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Keywords: PheRS
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Journal Articles
In collection:
Drosophila as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (3): dmm048132.
Published: 18 March 2021
.... Phenylalanyl tRNA synthetase (PheRS/FARS) levels are elevated in multiple cancers compared to their normal cell counterparts. Our results show that downregulation of PheRS, or only its α-PheRS subunit, reduces organ size, whereas elevated expression of the α-PheRS subunit stimulates cell growth...
Includes: Supplementary data