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Keywords: Peroxisome proliferator-activated receptor gamma (PPARγ)
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Journal Articles

Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ

Guoxi Li, Libin Zhou, Ying Zhu, Conghui Wang, Sha Sha, Xunde Xian, Yong Ji, George Liu, Ling Chen
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1615–1624.
https://doi.org/10.1242/dmm.021550
Published: 1 December 2015
...-nKO) mice display a depression-like phenotype with a reduced level of hippocampal peroxisome proliferator-activated receptor gamma (PPARγ). The present study investigated the influence of seipin deficiency on adult neurogenesis in the hippocampal dentate gyrus (DG) and the underlying mechanisms...
View articletitled, Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ
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Includes: Supplementary data