...Naoki Yoshida; Toshihiro Inubushi; Takumi Hirose; Gozo Aoyama; Hiroshi Kurosaka; Takashi Yamashiro ABSTRACT Cleft palate has a multifactorial etiology. In palatal fusion, the contacting medial edge epithelium (MEE) forms the epithelial seam, which is subsequently removed with the reduction of p63...

... is a prerequisite for anterior-specific palatal fusion. It was previously unclear, however, whether Cbfb served as a modulator or as an obligatory factor in the Runx signaling process that regulates palatogenesis. Here, we report that Cbfb is essential and indispensable in mouse anterior palatogenesis. Palatal...