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Keywords: Osteoarthritis
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Journal Articles
Dis Model Mech (2020) 13 (7): dmm044719.
Published: 14 July 2020
... and in osteoarthritis. Ccn2 null mice exhibit a range of skeletal dysmorphisms, highlighting its importance in regulating matrix formation during development; however, its role in adult cartilage remains unclear. The aim of this study was to determine the role of CCN2 in postnatal chondrocytes in models of post...
Journal Articles
In collection:
Metabolic Disorders
Dis Model Mech (2018) 11 (9): dmm034827.
Published: 31 August 2018
...Elise L. Donovan; Erika Barboza Prado Lopes; Albert Batushansky; Mike Kinter; Timothy M. Griffin ABSTRACT Obesity is one of the most significant risk factors for knee osteoarthritis. However, therapeutic strategies to prevent or treat obesity-associated osteoarthritis are limited because...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2015) 8 (1): 17–30.
Published: 1 January 2015
...Sarah Thysen; Frank P. Luyten; Rik J. U. Lories Osteoarthritis is a chronic degenerative disorder of the joint and represents one of the most common diseases worldwide. Its prevalence and severity are increasing owing to aging of the population, but treatment options remain largely limited...