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Keywords: Oligodendrocytes
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Journal Articles
Dis Model Mech (2021) 14 (8): dmm048925.
Published: 20 July 2021
... zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment . Nat. Commun. 4 , 2410 . 10.1038/ncomms3410 Baydyuk , M. , Morrison , V. E. , Gross , P. S. and Huang , J. K. ( 2020 ). Extrinsic factors driving oligodendrocyte lineage cell progression in CNS...
Journal Articles
Dis Model Mech (2020) 13 (9): dmm046243.
Published: 25 September 2020
... of Down syndrome reveal phenotypic variability affecting neurodevelopment and learning and memory behaviors, calling into question the validity of this model. Developmental disorders Brain development Milestones Adult behavior Oligodendrocytes Samples for gene expression analysis...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2015) 8 (12): 1591–1601.
Published: 1 December 2015
... and a hypoplastic corpus callosum are the major hallmarks of MLIV brain pathology. Here, we report that loss of TRPML1 in mice results in developmental aberrations of brain myelination as a result of deficient maturation and loss of oligodendrocytes. Defective myelination is evident in Mcoln1 −/− mice at postnatal...
Includes: Supplementary data