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Keywords: Neurogenesis
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Journal Articles

Postnatal Zika virus infection leads to morphological and cellular alterations within the neurogenic niche

In collection:
Infectious disease biology
Jéssica C. C. G. Ferreira, Raissa R. Christoff, Tailene Rabello, Raiane O. Ferreira, Carolina Batista, Pedro Junior Pinheiro Mourão, Átila D. Rossi, Luiza M. Higa, Maria Bellio, Amilcar Tanuri, Patricia P. Garcez
Journal: Disease Models & Mechanisms
Dis Model Mech (2024) 17 (2): dmm050375.
https://doi.org/10.1242/dmm.050375
Published: 28 February 2024
.... Brain development Dentate gyrus Congenital malformation Congenital Zika syndrome Hippocampus Microcephaly Neurogenesis Subgranular zone Zika virus Conselho Nacional de Desenvolvimento Científico e Tecnológico http://dx.doi.org/10.13039/501100003593 Coordenação de...
View articletitled, Postnatal Zika virus infection leads to morphological and cellular alterations within the neurogenic niche
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Includes: Supplementary data
Journal Articles

Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival

In collection:
Cancer , Drosophila as a Disease Model
Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-Garcia, Ruth H. Palmer
Journal: Disease Models & Mechanisms
Dis Model Mech (2022) 15 (8): dmm049591.
https://doi.org/10.1242/dmm.049591
Published: 16 August 2022
... , R. et al. ( 2014 ). Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma . Oncotarget 5 , 2688 - 2702 . 10.18632/oncotarget.1883 Chand , D. , Yamazaki , Y. , Ruuth , K. , Schönherr , C...
View articletitled, Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival
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Includes: Supplementary data
Journal Articles

Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder

In collection:
Neurodegenerative Disorders
Ekaterina Savchenko, Yajuvinder Singh, Henna Konttinen, Katarina Lejavova, Laura Mediavilla Santos, Alexandra Grubman, Virve Kärkkäinen, Velta Keksa-Goldsteine, Nikolay Naumenko, Pasi Tavi, Anthony R. White, Tarja Malm, Jari Koistinaho, Katja M. Kanninen
Journal: Disease Models & Mechanisms
Dis Model Mech (2017) 10 (9): 1089–1100.
https://doi.org/10.1242/dmm.029165
Published: 1 September 2017
...) generate new neurons in the brain throughout an individual's lifetime in an intricate process called neurogenesis. Neurogenic alterations are a common feature of several adult-onset neurodegenerative diseases. The neuronal ceroid lipofuscinoses (NCLs) are the most common group of inherited...
View articletitled, Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder
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Journal Articles

Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ

Guoxi Li, Libin Zhou, Ying Zhu, Conghui Wang, Sha Sha, Xunde Xian, Yong Ji, George Liu, Ling Chen
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1615–1624.
https://doi.org/10.1242/dmm.021550
Published: 1 December 2015
...-nKO) mice display a depression-like phenotype with a reduced level of hippocampal peroxisome proliferator-activated receptor gamma (PPARγ). The present study investigated the influence of seipin deficiency on adult neurogenesis in the hippocampal dentate gyrus (DG) and the underlying mechanisms...
View articletitled, Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ
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Includes: Supplementary data