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Keywords: Neurite extension
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Journal Articles
Xiaohua Xu, Aleksandar Denic, Luke R. Jordan, Nathan J. Wittenberg, Arthur E. Warrington, Bharath Wootla, Louisa M. Papke, Laurie J. Zoecklein, Daehan Yoo, Jonah Shaver, Sang-Hyun Oh, Larry R. Pease, Moses Rodriguez
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (8): 831–842.
Published: 1 August 2015
... disease that primarily affects spinal cord anterior horn cells and their axons for which there is no treatment. Here we report the use of a recombinant natural human IgM that binds to the surface of neurons and supports neurite extension, rHIgM12, as a therapeutic strategy in murine models of human ALS...
Includes: Supplementary data