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Keywords: Neural crest cell
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Journal Articles
Stanley M. Kanai, Caleb Heffner, Timothy C. Cox, Michael L. Cunningham, Francisco A. Perez, Aaron M. Bauer, Philip Reigan, Cristan Carter, Stephen A. Murray, David E. Clouthier
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (4): dmm049320.
Published: 29 April 2022
... to multiple genetic variants in the coding sequence of phospholipase C β4 ( PLCB4 ). PLCB4 is a direct signaling effector of the endothelin receptor type A (EDNRA)-Gq/11 pathway, which establishes the identity of neural crest cells (NCCs) that form lower jaw and middle ear structures. However, the functional...
Includes: Supplementary data