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Keywords: Negative geotaxis
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Journal Articles
Stephanie M. Pütz, Jette Kram, Elisa Rauh, Sophie Kaiser, Romy Toews, Yi Lueningschroer-Wang, Dirk Rieger, Thomas Raabe
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (6): dmm047811.
Published: 14 June 2021
... disease Mbt PAK4 Negative geotaxis Sleep fragmentation Life expectancy Emotional behavior Dopaminergic PAM cluster neurons Parkinson's disease (PD) is a common neurodegenerative disease and the most prevalent movement disorder. PD is mainly characterized by motor symptoms...
Includes: Supplementary data
Journal Articles
Laura Tamberg, Mariliis Jaago, Kristi Säälik, Alex Sirp, Jürgen Tuvikene, Anastassia Shubina, Carl Sander Kiir, Kaja Nurm, Mari Sepp, Tõnis Timmusk, Mari Palgi
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (7): dmm042747.
Published: 30 July 2020
... and the modulation of Da levels alter the levels of Syn and dlg1 mRNA. Silencing of da also affects negative geotaxis of the adult flies, suggesting the impairment of locomotor function. Overall, our findings suggest that Da regulates Drosophila larval memory and adult negative geotaxis, possibly via its synaptic...
Includes: Supplementary data