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Keywords: Necrotizing enterocolitis
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Journal Articles
Dis Model Mech (2020) 13 (8): dmm044776.
Published: 27 August 2020
... Necrotizing enterocolitis Neonatal mouse model Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disease in preterm infants, characterized by abdominal distension, feeding intolerance, inflammation, intestinal necrosis and bloody stools. It is one of the leading causes...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2020) 13 (6): dmm044388.
Published: 24 June 2020
...Mark L. Kovler; Chhinder P. Sodhi; David J. Hackam ABSTRACT Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in premature infants and remains stubbornly difficult to treat in many cases. Much of our understanding of NEC pathogenesis has been gained through...
Journal Articles
Dis Model Mech (2019) 12 (12): dmm040998.
Published: 09 December 2019
...Yong Chen; Yuhki Koike; Lijun Chi; Abdalla Ahmed; Hiromu Miyake; Bo Li; Carol Lee; Paul Delgado-Olguín; Agostino Pierro ABSTRACT Major risk factors for necrotizing enterocolitis (NEC) are formula feeding and prematurity; however, their pathogenic mechanisms are unknown. Here, we found...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2017) 10 (6): 727–736.
Published: 01 June 2017
...Jessica R. White; Huiyu Gong; Brock Pope; Patrick Schlievert; Steven J. McElroy ABSTRACT Necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality in premature infants. Both human surgical specimens and animal models suggest a potential involvement of Paneth cells in NEC...