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Keywords: NSCLC
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Journal Articles

RET inhibition in novel patient-derived models of RET fusion- positive lung adenocarcinoma reveals a role for MYC upregulation

Open Access
In collection:
Cancer
Takuo Hayashi, Igor Odintsov, Roger S. Smith, Kota Ishizawa, Allan J. W. Liu, Lukas Delasos, Christopher Kurzatkowski, Huichun Tai, Eric Gladstone, Morana Vojnic, Shinji Kohsaka, Ken Suzawa, Zebing Liu, Siddharth Kunte, Marissa S. Mattar, Inna Khodos, Monika A. Davare, Alexander Drilon, Emily Cheng, Elisa de Stanchina, Marc Ladanyi, Romel Somwar
Journal: Disease Models & Mechanisms
Dis Model Mech (2021) 14 (2): dmm047779.
https://doi.org/10.1242/dmm.047779
Published: 11 February 2021
... lung cancer (NSCLC) . J. Clin. Oncol. 37 , 9008 - 9008 . 10.1200/JCO.2019.37.15_suppl.9008 Gautschi , O. , Milia , J. , Filleron , T. , Wolf , J. , Carbone , D. P. , Owen , D. , Camidge , R. , Narayanan , V. , Doebele , R. C. , Besse , B. et al...
View articletitled, RET inhibition in novel patient-derived models of RET fusion- positive lung adenocarcinoma reveals a role for MYC upregulation
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Includes: Supplementary data
Journal Articles

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

Open Access
In collection:
Cancer
Yongjun Yin, Xiaodi Ren, Craig Smith, Qianxu Guo, Maria Malabunga, Ilhem Guernah, Yiwei Zhang, Juqun Shen, Haijun Sun, Nabil Chehab, Nick Loizos, Dale L. Ludwig, David M. Ornitz
Journal: Disease Models & Mechanisms
Dis Model Mech (2016) 9 (5): 563–571.
https://doi.org/10.1242/dmm.024760
Published: 1 May 2016
... of human cancer and in congenital birth defects. In human lung cancer, fibroblast growth factor 9 (FGF9), a high-affinity ligand for FGFR3, is overexpressed in 10% of primary resected non-small cell lung cancer (NSCLC) specimens. Furthermore, in a mouse model where FGF9 can be induced in lung epithelial...
View articletitled, Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody
Open the PDF for Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody in another window
Includes: Supplementary data