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Keywords: NMJ
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Journal Articles
Dis Model Mech (2018) 11 (4): dmm031997.
Published: 16 April 2018
... extensor digitorum longus muscle following intrathecal injection of ALS-CSF. Adenosine triphosphatase staining and electron microscopic (EM) analysis revealed significant atrophy and grouping of type 2 fibres in ALS-CSF-injected rats. Profound neuromuscular junction (NMJ) damage, such as fragmentation...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2014) 7 (3): 373–385.
Published: 1 March 2014
... and BACE in the central nervous system of the fly. Here we describe synaptic defects in the larval neuromuscular junction (NMJ) in this model. Our results indicate that expression of human APP and BACE at the larval NMJ leads to defective larval locomotion behavior, decreased presynaptic connections...
Includes: Supplementary data