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Keywords: Myosin heavy chain
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Journal Articles
In collection:
Drosophila as a Disease Model
Jennifer A. Suggs, Girish C. Melkani, Bernadette M. Glasheen, Mia M. Detor, Anju Melkani, Nathan P. Marsan, Douglas M. Swank, Sanford I. Bernstein
Journal:
Disease Models & Mechanisms
Dis Model Mech (2017) 10 (6): 761–771.
Published: 1 June 2017
... severe in adulthood. The disease arises from an autosomal dominant point mutation causing an E706K substitution in myosin heavy chain type IIa. We have previously expressed the corresponding myosin mutation (E701K) in homozygous Drosophila indirect flight muscles and recapitulated the myofibrillar...
Includes: Supplementary data
