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Keywords: Mutations
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Journal Articles
In collection:
C. elegans as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (6): dmm050079.
Published: 6 June 2023
... to identify components of glycolysis and electron transport chain complexes ( Zhao et al., 2013 ; Luz et al., 2016 ). Besides this arsenic-induced model, a Warburg-like aberrant glycolysis has been studied in a C. elegans strain carrying mutant sdhb-1 that mimics a missense mutation of the human...
Includes: Supplementary data
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2017) 10 (7): 923–929.
Published: 1 July 2017
... that the spatiotemporal pattern of Cic during this signaling event can be harnessed for functional studies of mutations in the Ras pathway in human diseases. Our approach relies on a new microfluidic device that enables parallel imaging of Cic dynamics in dozens of live embryos. We found that although the pattern of Cic...
Includes: Supplementary data