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Keywords: Muscle atrophy
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Journal Articles

Sporadic amyotrophic lateral sclerosis (SALS) – skeletal muscle response to cerebrospinal fluid from SALS patients in a rat model

In collection:
Neurodegenerative Disorders
Shruthi Shanmukha, Gayathri Narayanappa, Atchayaram Nalini, Phalguni Anand Alladi, Trichur R. Raju
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (4): dmm031997.
https://doi.org/10.1242/dmm.031997
Published: 16 April 2018
...Shruthi Shanmukha; Gayathri Narayanappa; Atchayaram Nalini; Phalguni Anand Alladi; Trichur R. Raju ABSTRACT Skeletal muscle atrophy is the most prominent feature of amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease of motor neurons. However, the contribution of skeletal...
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Includes: Supplementary data
Journal Articles

Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy

Franziska Lang, Sriram Aravamudhan, Hendrik Nolte, Clara Türk, Soraya Hölper, Stefan Müller, Stefan Günther, Bert Blaauw, Thomas Braun, Marcus Krüger
Journal: Disease Models & Mechanisms
Dis Model Mech (2017) 10 (7): 881–896.
https://doi.org/10.1242/dmm.028910
Published: 1 July 2017
... skeletal muscle atrophy reveals that complex regulatory networks are activated during muscle wasting. Muscle atrophy Denervation Pulsed SILAC Ubiquitination Random forest Numerous experiments have demonstrated that the metabolic and contractile properties of skeletal muscles can change...
View articletitled, Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy
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Includes: Supplementary data
Journal Articles

Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model

Ariadna Bargiela, Estefanía Cerro-Herreros, Juan M. Fernandez-Costa, Juan J. Vilchez, Beatriz Llamusi, Ruben Artero
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (7): 679–690.
https://doi.org/10.1242/dmm.018127
Published: 1 July 2015
... attributed. Summary: Increased apoptosis and autophagy are processes that lead to muscle mass wasting in DM1, which is one of the most debilitating symptoms of the disease. Autophagy Apoptosis Muscleblind CTG repeat expansion Muscle atrophy Dystrophy Myotonic dystrophy type 1 (DM1...
View articletitled, Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model
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Includes: Supplementary data