... in neurons and support the involvement of mitochondrial dysfunction in BBSOAS pathogenesis. * Authors for correspondence ( [email protected] ; [email protected] ) Handling Editor: Rickie Patani Competing interests The authors declare no competing or financial interests...

... , J. M. and Melov , S. ( 2013 ). SOD2 in mitochondrial dysfunction and neurodegeneration . Free Radic. Biol. Med. 62 , 4 - 12 . 10.1016/j.freeradbiomed.2013.05.027 Gao , B. , Yang , L. and Luo , Z. J. ( 2014 ). Transdifferentiation between bone and fat on bone...

...Manuel J. Del Rey; Carolina Meroño; Cristina Municio; Alicia Usategui; María Mittelbrunn; Inés García-Consuegra; Gabriel Criado; José L. Pablos ABSTRACT Mitochondrial dysfunction associates with several pathological processes and contributes to chronic inflammatory and ageing-related diseases...

... demonstrated that PPX exerts neuroprotection through mitochondria. However, the neuromodulator-related effects of PPX against traumatic brain injury (TBI) remain unexplored. The present study, therefore, investigated the mechanism of neuroprotection by PPX against oxidative stress, mitochondrial dysfunction...

... dysfunction have been well developed in this organism. Unlike mammalian systems, Dictyostelium mitochondrial dysfunction causes a reproducible and readily assayed array of aberrant phenotypes: defective phototaxis, impaired growth, normal rates of endocytosis and characteristic defects in multicellular...