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Keywords: Minocycline
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Journal Articles
In collection:
Neurodegenerative Disorders
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (9): dmm033597.
Published: 5 September 2018
... retinal degeneration, microglial activation, deposition of autofluorescent material and transcriptomic changes compared to wild-type animals. Finally, we treated the light-exposed Cln3 Δex7/8 animals with the immunomodulatory compound minocycline, and thereby rescued the retinal phenotype and diminished...
Includes: Supplementary data
