... erythropoiesis and megakaryopoiesis, reduced bone density, craniofacial changes, altered cardiac function, a pre-diabetic state, and deficits in memory, locomotion, hearing and sleep. Thus, Dp1Tyb mice are an excellent model for investigating complex DS phenotype-genotype relationships for this common disorder...

... the role of individual subunits of this large protein complex using targeted RNA interference in post-mitotic memory-forming neurons of the Drosophila mushroom body (MB). Knockdown flies were tested for defects in MB morphology, short-term memory and long-term memory. Using this approach, we identified...

... ). Inverted-U-shaped dopamine actions on human working memory and cognitive control . Biol. Psychiatry   69 , e113 - e125 . 10.1016/j.biopsych.2011.03.028 Cui , K. , Ashdown , H. , Luheshi , G. N. and Boksa , P. ( 2009 ). Effects of prenatal immune activation on hippocampal...